Keanu Reeves

Kai

Hiroyuki Sanada

Kuranosuke Ôishi

Ko Shibasaki

Mika

Tadanobu Asano

Lord Kira

Min Tanaka

Lord Asano

Rinko Kikuchi

Witch

Jin Akanishi

Chikara

Masayoshi Haneda

Yasuno

Hiroshi Sogabe

Hazama

Takato Yonemoto

Basho

Shû Nakajima

Horibe

Hiroshi Yamada

Hara

Cary-Hiroyuki Tagawa

Shogun Tsunayoshi

Tanroh Ishida

Shogun's Adjutant

Yorick van Wageningen

Kapitan

Ron Bottitta

Narrator

Natsuki Kunimoto

Riku

Togo Igawa

Tengu Lord

Akira Koieyama

Kira's Spy

Haruka Abe

Mika's Handmaiden

Clyde Kusatsu

Drunk Official

Junichi Kajioka

Guard

Masashi Fujimoto

Lead Soldier

Neil Fingleton

Lovecraftian Samurai

Rick Genest

Foreman

Masayuki Deai

Isogai