Keanu Reeves

John Constantine

Rachel Weisz

Angela Dodson / Isabel Dodson

Shia LaBeouf

Chas Kramer

Djimon Hounsou

Midnite

Max Baker

Beeman

Pruitt Taylor Vince

Father Hennessy

Gavin Rossdale

Balthazar

Tilda Swinton

Gabriel

Peter Stormare

Lucifer

Jesse Ramirez

Scavenger

José Zúñiga

Detective Weiss

April Grace

Dr. Leslie Archer

Larry Cedar

Vermin Man

Francis Guinan

Father Garret

Suzanne Whang

Mother

Jhoanna Trias

Possessed Girl

Alice Lo

Old Woman

Nicholas Downs

Church Attendant

Tanoai Reed

Midnite Bouncer

Quinn Buniel

10 Year-Old Constantine

Ann Ryerson

Old Woman on Bus

Stephanie Fabian

Molly's Server

Connor Dylan Wryn

Teenage Constantine

Laz Alonso

Morgue Security Guard

Jeremy Ray Valdez

Liquor Store Clerk Nico

Jose Molina

Scavenger #2

Barbara Pilavin

Old Woman on Bus (Demon)

C.W. Pyun

Korean Man

Sharon Omi

Female Tenant

Edward J. Rosen

Liquor Store Clerk

John Gipson

Smoking Man

Roberto Kawata

Police Officer

Michelle Monaghan

Ellie (uncredited)

R.A. Rondell

Man in Jeep (uncredited)

Chad Stahelski

Demon in Hospital (uncredited)

Kevin Alejandro

Border Patrol (uncredited)