Kristen Wiig

Annie

Maya Rudolph

Lillian

Rose Byrne

Helen

Chris O'Dowd

Rhodes

Melissa McCarthy

Megan

Wendi McLendon-Covey

Rita

Ellie Kemper

Becca

Jill Clayburgh

Annie's Mom

Matt Lucas

Gil

Rebel Wilson

Brynn

Michael Hitchcock

Don Cholodecki

Terry Crews

Boot Camp Instructor

Tom Yi

Jewelry Store Couple

Elaine Kao

Jewelry Store Couple

Kali Hawk

Kahlua

Joe Nuñez

Oscar the Security Guard

Greg Tuculescu

Kevin

Steve Bannos

Annie's Mistaken Husband

Hugh Dane

Annie's Mistaken Fella

Franklyn Ajaye

Lillian's Dad

Tim Heidecker

Dougie

Lynne Marie Stewart

Lillian's Mom

Andy Buckley

Helen's Husband

Molly Buffington

Helen's Stepdaughter

Matt Bennett

Helen's Stepson

Nancy Carell

Helen's Tennis Partner

Melanie Hutsell

Annie's Tennis Partner

Eloy Casados

Churra Chi Waiter

Jessica St. Clair

Whitney

Dana Powell

Flight Attendant Claire

Mitch Silpa

Flight Attendant Steve

Annie Mumolo

Nervous Woman on Plane

Ben Falcone

Air Marshall Jon

Angelica Acedo

Flight Attendant in Coach

Mia Rose Frampton

13 Year Old Girl in Jewelry Store

Joel Madison

13 Year Old Girl's Father

R.F. Daley

Butler

Jordan Black

Horseman

David Hoffman

Doorman at Shower

Jillian Bell

Girl at Shower

Ariane Price

Girl at Shower

Frederik Hamel

Shower Waiter

Richard Riehle

Bill Cozbi

Jimmy Brogan

Minister

Carnie Wilson

Carnie Wilson

Chynna Phillips

Chynna Phillips

Wendy Wilson

Wendy Wilson

Jon Hamm

Ted (uncredited)

Brian Petsos

Pete (uncredited)

Blake Garrett Rosenthal

Tyler (uncredited)

Paul Feig

Wedding Guest (uncredited)

Pat Carroll

Old Woman in Car (uncredited)

Suzanne LaChasse

Hostess (uncredited)

Owen Daniels

Obnoxious Ice Skater (uncredited)

Greg Worswick

Valet (uncredited)

Joyce Lakin

Lillian's Aunt (uncredited)