What is it that motivates someone to ride a bicycle all the way across the United States?

Mark Vashro travels by bicycle from Boston to San Diego through the southern regions of the United States. As he travels, he meets fascinating people and asks them how they ended up where they are. He meets Dave, an alcoholic from Virginia who is trying to reach his family in North Carolina. A woman in New Orleans who used to be an acclaimed designer in New York but realized it wasn't the right life for her. A fisherman living in a self built, single room house in the marshes of Louisiana, wondering how the oil spill will affect his life. These people along with amazing experiences and scenery tell a story of great adventure and human experience.