Ian McKellen

Sherlock Holmes

Laura Linney

Mrs. Munro

Milo Parker

Roger

Hiroyuki Sanada

Tamiki Umezaki

Roger Allam

Dr. Barrie

Frances de la Tour

Madame Schirmer

Hattie Morahan

Ann Kelmot

Phil Davis

Inspector Gilbert

Patrick Kennedy

Thomas Kelmot

John Sessions

Mycroft Holmes

Frances Barber

Matinee "Madame Schirmer"

Charles Maddox

Oswald

Takako Akashi

Maya Umezaki

Zak Shukor

Masuo Umezaki

Michael Culkin

Bank Manager

David Foxxe

Chemist

Oliver Devoti

Ticket Agent

Mike Burnside

Ann's Solicitor

Nicholas Rowe

Matinee "Sherlock Holmes"

Sam Coulson

Matinee "Thomas Kelmot"

Hermione Corfield

Matinee "Ann Kelmot"

Kit Connor

Boy

Zoe Rainey

Boy's Mother

Eileen Davies

Lady on Platform

Colin Starkey

Dr. John Watson

Sarah Crowden

Mrs. Hudson

Elizabeth Jane Cassidy

Waitress (uncredited)

John Carr

Patron in Cinema (uncredited)

Johnny Otto

Army Officer (uncredited)

Paul Blackwell

Station Passenger