Basil Rathbone

Sherlock Holmes

Nigel Bruce

Doctor Watson

Evelyn Ankers

Kitty

Reginald Denny

Sir Evan Barham

Thomas Gomez

R.F. Meade

Henry Daniell

Sir Anthony Lloyd

Montagu Love

General Jerome Lawford

Olaf Hytten

Admiral Sir John Fabian Prentiss

Leyland Hodgson

Captain Roland Shore

Mary Gordon

Mrs. Hudson

Hillary Brooke

Jill Grandis

Harry Cording

Camberwell

Herbert Evans

Smithson - Barham's Butler (uncredited)

Fred Graham

Meade's Henchman (uncredited)

Gavin Muir

BBC Radio Announcer (voice) (uncredited)

Edgar Barrier

Voice of Terror (voice) (uncredited)

Bobby Hale

Bar Patron (uncredited)