George Clooney

Chris Kelvin

Natascha McElhone

Rheya

Viola Davis

Gordon

Jeremy Davies

Snow

Ulrich Tukur

Gibarian

Michael Ensign

Friend

John Cho

DBA Emissary

Morgan Rusler

DBA Emissary

Shane Skelton

Gibarian's Son

Donna Kimball

Mrs. Gibarian

Elpidia Carrillo

Friend

Kent Faulcon

Patient

Lauren Cohn

Patient

Jennie Baek

Passenger (uncredited)

Tony Clemons

Dinner Guest (uncredited)

Annie Morgan

Nurse (uncredited)

Antonio Rochira

Party Guest (uncredited)

Jude S. Walko

City Dweller (uncredited)