Charlie Sheen

Charlie B. Barkin (voice)

Dom DeLuise

Itchy Itchiford (voice)

Adam Wylie

David (voice)

Sheena Easton

Sasha La Fleur (voice)

Ernest Borgnine

Carface (voice)

George Hearn

Red (voice)

Bebe Neuwirth

Anabelle (voice)

Hamilton Camp

Chihuahua (voice)

Steve Mackall

Short Customs Dog (voice)

Dan Castellaneta

Tall Customs Dog / Angel Dog #1 (voice)

Tony Jay

Reginald (voice)

Jim Cummings

Jingles (voice)

Wallace Shawn

Labrador MC (voice)

Kevin Michael Richardson

St. Bernard / Officer Andrews (voice)

Pat Corley

Officer McDowell (voice)

Maurice LaMarche

Lost & Found Officer (voice)